Competition Open: CIHR Operating Grant–ECRs in Human Development, Child and Youth Health

Competition Open: CIHR Operating Grant–ECRs in Human Development, Child and Youth Health

CIHR Operating Grant (2024)

Early Career Researchers in Human Development, Child and Youth Health


Funding Objectives

  • Support early career researchers in initiating and conducting independent research in human development, child and youth health with the goal of building research capacity in this important health research area.
  • Generate new knowledge that will contribute to improving human development, child and youth health outcomes, promote health equity, and increase our understanding of the challenges, needs and current gaps in this research area.
  • Facilitate knowledge exchange and translation between early career researchers and other stakeholders in human development, child and youth health.

Funds Available

  • Maximum amount per grant is $50,000 per year for up to 3 years (total of $150,000 per grant)
  • Total amount available is $1,800,000, enough to fund ~12 grants. This amount may increase if additional funding partners participate.
    • Of the $1,800,000:
      • $1,200,000 is available to fund 8 applications relevant to the overall purpose of the funding opportunity.
      • $300,000 is available to fund 2 applications relevant to the Indigenous Human Development, Child and Youth Health pool.
      • $300,000 is available to fund 2 applications relevant to the Human Development, Child and Youth Health for Equity-Deserving Groups pool.
      • Applications relevant to each pool will be funded top down in order of ranking. Remaining applications in the competition will be pooled together and funded in rank order. If a pool is undersubscribed or lacks fundable applications, funds will be rolled into the general competition pool.

Research Areas

  • In addition to supporting projects relevant to human development, child and youth health in IHDCYH’s mandate area, separate funding pools will support the following priority areas:
  • Indigenous Human Development, Child and Youth Health: This funding pool will support distinctions-based research that focuses on human development, child and youth health in First Nations, Inuit, and Métis peoples and/or communities.
  • Human Development, Child and Youth Health for Equity-Deserving Groups*: This funding pool will support research that focuses on human development, child and youth health in equity-deserving groups. Equity-deserving groups include, but are not limited to, women, persons with disabilities, members of visible minority/racialized groups and members of 2SLGBTQI+ communities.

*Please note that projects focused on Indigenous (First Nations, Inuit or Métis) human development, child and youth health must apply to the Indigenous Human Development, Child and Youth Health pool. Projects that include Indigenous people in a broader sample of equity-deserving groups must apply to the Human Development, Child and Youth Health for Equity-Deserving Groups pool.

Eligibility

  • All 9 eligibility requirements (listed here) must be met. For example:
    1. The Nominated Principal Applicant (NPA) must:
      • be an early career researcher affiliated with a Canadian postsecondary institution and/or its affiliated institutions (including hospitals, research institutes and other non-profit organizations with a mandate for health research and/or knowledge translation) and
      • have at least 50% protected time for research

Evaluation Criteria

  • Research Approach
  • Originality of the Proposal
  • Applicant
  • Impact of Research
  • Quality of the Research Environment

Key Dates

For full information and details about this competition, including how yo apply, please visit the ResearchNet page. Deadlines are linked above in the ATM Calendar.

Dr. Sorensen, Director of the Academy of Translational Medicine, co-authors promising research regarding cancer-causing proteins.

Applications Open: 2024 C2 & Reach Competitions

The 2024 Convening & Collaborating (C2) and Reach competitions are now open for applications

C2: Promote knowledge exchange and meaningful collaboration

  • Supports researchers, trainees and those who use research to engage with each other and co-develop research that is impactful for patients, health practitioners and policymakers.
  • Researchers who need support to develop a research agenda, identify key research practice priorities or evaluate a peer support initiative should consider applying to the C2 program. 

Reach: Disseminate research evidence with research users 

  • Supports researchers build knowledge translation capacity through events, activities and tools that reach audiences that can improve health and care for British Columbians and their communities. Supports researchers to disseminate research evidence by co-developing events, activities and tools with those who can directly benefit from it. This helps researchers reach audiences who can use the knowledge to ultimately improve health and care for British Columbians and their communities.
  • Researchers who need support to disseminate their research through events, activities or tools should consider applying to the Reach program.

 Program Details

  • For the 2024 C2 & Reach competitions, Health Research BC will continue to accept applications from across the full range of health research topics.
  • Additional funding is also available this year to support proposals focused on 4 priority areas:
      1. Population aging
      2. Climate change & health
      3. Health human resources crisis
      4. Public health emergencies
  • The maximum amount for each award has increased to $20,000

Key Dates

  • Information Session Webinar: 10 April 2024 | 10:30am
  • Application Deadlines
    • Applicant: 13 May 2024
    • Host Institution: 21 May 2024
  • Anticipated notice of funding decision:September 2024
  • Award start date: 1 October 2024

Find the Health Research BC announcement here

Find C2 competition details, eligibility requirements and information on how to apply, here

Find Reach competition details, eligibility requirements and information on how to apply, here

Globe and Mail article highlights ATM and ATM Director Dr. Poul Sorensen

The Acacdemy of Translational Medicine (ATM) and ATM Director Dr. Poul Sorensen have been highlighted in an article by The Globe and Mail.

The article, B.C. biotech boom: Vancouver looks to join the global big leagues of modern medicine, highlights, provides a inside look at Vancouver’s role in the global biotech industry. At the forefront of this conversation are the key players and spin-off companies that have created a dynamic landscape over the years, many of whom have UBC affiliations. For example, Dr. Pieter Cullis’ role in COVID-19 vaccines, and companies such as AbCellera and Aspect Biosystems. Both the ATM and Dr. Sorensen were mentioned in the article, with reference to how the ATM fits within the local ecosystem and how Dr. Sorensen has himself contributed to cutting-edge research with real-world impact.

‘Enabling UBC academics to think commercially is the goal of UBC’s Academy of Translational Medicine, created at Dr. Kelleher’s behest in 2019. His choice to lead it was intentional: celebrated UBC researcher Poul Sorensen, who discovered a gene mutation in 1998 linked to cancer.’

When Dr. Sorensen was interviewed for the article, he admitted that When we made the discovery we weren’t thinking about intellectual property”  and “If I had thought about it earlier I would have staked a claim. I thought, ‘Next time I do this, I’ll be smart.”

‘He only realized it when Bayer AG offered to fly him business class to give talks about his discoveries in the 2010s. At the time, the company was co-developing a drug to target the gene defect and shrink a range of tumours, which it expects will generate €750-million in yearly peak sales.’

However, author Sean Silcoff also addresses the the unique challenges that biotech faces in Vancouver, where there is a plethora of talent and is growing quickly, but it hasn’t quite been leveraged its full potential. One of Dr. Sorensen’s quotes in the article summed this up succinctly “We’re really good at discovery science in Vancouver. All the pieces are in place. Now, how do we up the game?”. Dr. Sorensen points out that  We’ve realized a lot of academics aren’t clear on when something will be of interest” (to the market), leading to the development of courses that aim to give academics the tools to file their new drug applications with regulators.

The ATM highly recommends reading this article for the full scope of information presented. The article can be found here through UBC’s Faculty of Medicine, or here on The Globe and Mail.

BCCHR Investigator Grant Award Program (IGAP) Announces Open Call for Clinician Scientists

The BC Children’s Hospital Research (BCCHR) Investigator Grant Award Program (IGAP) has announced an Open Call competition to support up to 2 new salary awards at the Clinician Scientist level, each at a maximum of $134,000 per year for 5 years. The IGAP Award ‘is intended to support existing Clinician Scientists who are looking to further develop and grow their research programs with the support of salary funding towards dedicated research time’.

Quick Facts

  • Clinician Scientists for this award are considered those who are or will be Research-primary and also provide clinical service.
    • This includes researchers who are also medical or allied health professions (ex: Emergency Department Physicians, Nurses, Physiotherapists, Psychologists, etc.).
  • The clinician scientist must currently hold an active clinical position and will continue to work clinically for approximately 30% alongside IGAP Award.
  • The clinician scientists awarded must have a minimum of 70% protected research time.
  • The candidate needs to be actively engaged in child health research and conduct a significant portion of their research on the BCCH Oak Street Campus.
  • Per year, the average IGAP Clinician Scientists Award holder:
    • Publishes 10 publications
    • Has 5 active grants
    • Supports 4 trainees

Applications

  • Application Deadline: 10 May 2024 | 4pm
    • Note: Applications may only be submitted by the Department/ School (not the individual Clinician Scientists), with each Department/School limited to 3 applications.
  • A completed application package includes:
    • Application Form
    • Clinician Scientist’s CV
    • Letter of commitment
    • Letts of support from partners (optional)

Visit here for full IGAP Award details, criteria, application requirements, and FAQ

The Weston Family Foundation Rapid Response 2024 Program

The Rapid Response project is designed to provide seed funding to catalyze novel, high-risk, high-reward translational research that accelerates the development of therapeutics or tools for neurodegenerative diseases of aging (NDAs).

  • Therapeutics should address unmet needs in the prevention, treatment and/or symptomatic management of NDAs.
  • Tools should address challenges in translational research to accelerate the development and/or clinical implementation of therapeutics for NDAs (e.g., biomarkers, drug delivery systems). Projects covering only the discovery/identification of a tool are considered out of scope.
  • Projects should also have preliminary data to support the hypothesis and feasibility of the project.

Funding Available

  • Up to $300,000 over a 18-24 month term

Key Dates

  • LOI Deadline
    • 30 April 2024
    • 11am PDT
  • Award Announcement
    • November 2024

Full program details and application instructions can be found here

Podcast Episode | From Mentee to Mentor: How to Help Trainees Thrive

Successful Session on Adaptive Trial Designs in the ATM’s Regulatory Sciences and Health Economics Course

The ATM brings together leading scientists to teach novel regulatory science methodology that supports bringing new health innovations to patients sooner. In a recent live session, the ATM facilitated an engaging discussion on novel approaches to the design of clinical trials, drawing significant enthusiasm from learners in the ATM’s Regulatory Sciences and Health Economics course.

The session was presented by Dr. Jay Park, who is the Scientific Lead and Founder of Core Clinical Services, an Assistant Professor at McMaster University and a Methodologist with expertise in HEOR and clinical trial designs.

Dr. Park addressed the inherent limitations of conventional approaches by advocating for adaptive designs that allow trial modifications based on interim data analysis. This approach introduces a dynamic element into clinical trials, enabling adjustments to sample sizes, trial arms, and other parameters in response to accumulating data, thereby enhancing trial efficiency, ethical standards, and resource allocation.

The presentation covered various adaptive design types, including sequential designs, sample size re-assessment, and response adaptive randomization, each tailored to specific trial needs and outcomes. Emphasizing the intricate planning and collaboration required, he noted the necessity for comprehensive pre-trial simulations, adherence to predefined standards, and transparent reporting guidelines to maintain the scientific integrity and regulatory compliance of adaptive trials. Despite the complexity and increased resource demands of implementing adaptive designs, they have the potential to transform clinical research by offering more flexible and efficient methodologies for exploring medical interventions.

Following the session, the ATM received an influx of positive feedback. Many learners emphasized how eye-opening the topic was, and appreciated the exposure to novel clinical trial methods which are aiming to improve patient care in a more ethical and efficient manner, without sacrificing quality of data. Students also noted that the session provided them with a realization that regulatory agencies are among the various groups that would need to commit to using this design of clinical trials. The ATM thanks Jay Park for the engaging presentation!

If you are curious to learn about the Regulatory Sciences and Health Economics course and the Regulatory Affairs in the Life Sciences (RALS) Micro-credentials, visit the ATM Education page here.

What to Watch: MEDTalks | Cellular and Gene Therapies

Call for Applications: SBME Innovates

UBC’s School of Biomedical Engineering (SBME) is excited to announce the call for applications for SBME Innovates 2024 intake. This incubation hub is designed for early-stage life sciences ventures, offering FREE dedicated wet laboratory space, equipment, building services, and more.

SBME Innovates is a Life Sciences Incubator designed to accelerate biotech translation from bench to societal impact. Located in UBC’s Biomedical Research Centre, it’s a fully equipped wet lab space for early stage companies with big ideas. Ventures are hosted for  18-24 months, provided access to dedicated wet laboratory space, equipment, and building services, free of charge. This residency also connects ventures with the SBME community while giving them access to SBME communications channels to help bring awareness to their work.

Wet Lab Facilities available to each venture:

  • 3 benches sized 200 x 85cm
  • 1 CO2 incubator
  • 3 shared biosafety cabinets
  • One dedicated shelf in -80C
  • 1/2 of a full-size -20C freezer
  • 1/2 of a full-size 4C fridge

Eligibility

  • SBME Innovates welcomes applications from life science ventures within the UBC community with a focus on human health impact.
  • A referral from e@UBC, CDL/Sauder, or SBME is mandatory at the time of application.

Key Dates

  • Finalist companies notified
    • 17 April 2024
  • Finalists present to the Adjudication Committee
    • 24 April 2024
  • Results announced
    • 26 April 2024
  • Onboarding of new ventures into SBME Innovates
    • Early May