We are entering a golden age of biomedical discovery, where new classes of therapeutics are expected to transform human health and drive economic growth over the next century. With world-class biomedical researchers and a vibrant life sciences ecosystem, BC has a distinct opportunity to lead this global transformation and shape a more healthy, sustainable, and innovative future for British Columbia. Never before have we had access to as much information and as many tools to advance research discoveries. Yet, in spite of the accelerated pace of fundamental discoveries across all areas of biomedicine, the timeline for translating this knowledge into concrete improvements in clinical care, continues to lag dramatically. This is a challenge that we need to solve and conquer, if we want to be internationally competitive.